Brian I Rini Selected Research

Peptides (Polypeptides)

2/2017	Specific immunotherapy in renal cancer: a systematic review.
11/2016	IMA901, a multipeptide cancer vaccine, plus sunitinib versus sunitinib alone, as first-line therapy for advanced or metastatic renal cell carcinoma (IMPRINT): a multicentre, open-label, randomised, controlled, phase 3 trial.
11/2011	Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination.
2/2009	The HLA-A2-restricted PSMA peptide LLHETDSAV is poorly immunogenic in patients with metastatic prostate cancer.

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Brian I Rini Research Topics

Disease

281	Renal Cell Carcinoma (Grawitz Tumor) 04/2024 - 04/2002
143	Neoplasms (Cancer) 04/2024 - 02/2002
28	Disease Progression 02/2024 - 03/2004
24	Hypertension (High Blood Pressure) 12/2020 - 03/2006
21	Prostatic Neoplasms (Prostate Cancer) 11/2021 - 02/2002
20	Fatigue 02/2024 - 03/2006
18	Neoplasm Metastasis (Metastasis) 01/2021 - 06/2004
12	Kidney Neoplasms (Kidney Cancer) 08/2023 - 01/2007
11	COVID-19 12/2021 - 01/2020
10	Hypoxia (Hypoxemia) 10/2023 - 04/2004
6	Carcinoma (Carcinomatosis) 12/2018 - 12/2011
5	Hand-Foot Syndrome 10/2019 - 01/2012
5	Exanthema (Rash) 10/2016 - 03/2006
4	Melanoma (Melanoma, Malignant) 01/2022 - 11/2011
4	Proteinuria 01/2018 - 11/2008
4	Neutropenia 11/2016 - 06/2006
3	Nausea 02/2024 - 01/2012
3	Thrombosis (Thrombus) 01/2019 - 02/2011
3	Diarrhea 01/2018 - 01/2012
3	Anemia 01/2018 - 06/2006
3	Edema (Dropsy) 01/2018 - 12/2015
3	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 10/2016 - 01/2007
3	Hyperglycemia 10/2016 - 12/2009
2	Infections 12/2021 - 11/2021
2	Pneumonia (Pneumonitis) 05/2020 - 03/2014
2	Necrosis 01/2020 - 04/2014
2	Mucositis 10/2019 - 12/2010
2	Urinary Bladder Neoplasms (Bladder Cancer) 01/2019 - 01/2018
2	Clear-cell metastatic renal cell carcinoma 01/2018 - 05/2013

Drug/Important Bio-Agent (IBA)

94	Sunitinib (Sutent)FDA Link 02/2024 - 12/2005
76	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2024 - 04/2004
45	Axitinib (AG 013736)IBA 03/2024 - 12/2005
31	Immune Checkpoint InhibitorsIBA 04/2024 - 09/2016
29	NivolumabIBA 12/2022 - 05/2015
28	Bevacizumab (Avastin)FDA Link 02/2022 - 04/2004
24	Sorafenib (BAY 43-9006)FDA Link 10/2021 - 03/2006
23	Biomarkers (Surrogate Marker)IBA 04/2024 - 07/2007
23	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2024 - 01/2006
22	IpilimumabIBA 12/2022 - 03/2007
20	Tyrosine Kinase InhibitorsIBA 02/2024 - 02/2007
13	pembrolizumabIBA 02/2024 - 01/2019
11	CytokinesIBA 10/2019 - 05/2002
10	atezolizumabIBA 02/2022 - 01/2018
10	TOR Serine-Threonine KinasesIBA 10/2016 - 12/2005
10	Interferon-alpha (Interferon Alfa)IBA 03/2014 - 04/2004
8	AndrogensIBA 11/2021 - 05/2002
7	Hormones (Hormone)IBA 01/2020 - 02/2002
7	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 10/2019 - 01/2003
7	AntigensIBA 11/2011 - 02/2002
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2006
6	pazopanib FDA Link 03/2019 - 07/2012
6	temsirolimus FDA Link 03/2014 - 09/2006
6	Interleukin-2 (IL2)IBA 01/2012 - 05/2002
5	avelumabIBA 02/2024 - 01/2018
5	LigandsIBA 02/2022 - 11/2011
5	B7-H1 AntigenIBA 01/2022 - 01/2018
5	Angiogenesis InhibitorsIBA 03/2020 - 10/2006
5	VaccinesIBA 02/2017 - 02/2002
5	Everolimus FDA Link 10/2016 - 09/2006
5	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 12/2007 - 01/2006
5	Prostate-Specific Antigen (Semenogelase)IBA 03/2007 - 01/2003
4	tivozanibIBA 01/2024 - 01/2020
4	EnzymesIBA 01/2022 - 09/2006
4	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2021 - 01/2020
4	Peptides (Polypeptides)IBA 02/2017 - 02/2009
4	Imatinib Mesylate (Gleevec)FDA Link 10/2016 - 10/2006
4	MTOR InhibitorsIBA 06/2016 - 10/2008
4	Phosphotransferases (Kinase)IBA 02/2012 - 05/2006
3	cabozantinibIBA 10/2022 - 11/2015
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 02/2022 - 06/2006
3	Alanine Transaminase (SGPT)IBA 12/2020 - 01/2018
3	Monoclonal AntibodiesIBA 07/2020 - 02/2007
3	Lipase (Acid Lipase)FDA Link 10/2019 - 06/2006
3	ChemokinesIBA 10/2019 - 11/2011
3	Amylases FDA Link 10/2019 - 12/2015
3	Interleukin-8 (Interleukin 8)IBA 05/2017 - 02/2010
3	InterferonsIBA 01/2012 - 02/2009
3	Fluorouracil (Carac)FDA LinkGeneric 09/2008 - 10/2002
3	sipuleucel-T (APC8015)FDA Link 07/2006 - 02/2002
3	prostatic acid phosphataseIBA 07/2006 - 02/2002
2	cyclopropapyrroloindoleIBA 02/2024 - 01/2019
2	lenvatinibIBA 10/2023 - 10/2022
2	RNA (Ribonucleic Acid)IBA 11/2022 - 01/2021
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2020 - 03/2007
2	Immunoglobulin G (IgG)IBA 05/2020 - 01/2018
2	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2019
2	PT2385IBA 01/2020 - 01/2018
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2019 - 01/2006
2	human ALK1-Fc fusion proteinIBA 01/2019 - 07/2017
2	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 01/2018

Therapy/Procedure

175	Therapeutics 03/2024 - 02/2002
29	Immunotherapy 03/2024 - 06/2003
27	Nephrectomy 11/2023 - 06/2004
9	Aftercare (After-Treatment) 08/2023 - 12/2006
7	Drug Therapy (Chemotherapy) 01/2022 - 04/2002
6	Castration 01/2020 - 10/2002
4	Neoadjuvant Therapy 01/2019 - 01/2018
4	Molecular Targeted Therapy 01/2018 - 01/2007
3	Radiotherapy 03/2018 - 01/2003
2	Drug Tapering 01/2018 - 03/2015